Abstract Background For many gene structures it is impossible to resolve intensity data uniquely to establish abundances of splice variants.This was empirically noted by Wang et al.in which it Tents was called a "degeneracy problem".The ambiguity results from an ill-posed problem where additional information is needed in order to obtain an unique a
ABSTRACT Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans.It also increases fitness in the presence of fluconazole, but the underlying molecular mechanism is not understood.To address this question, we evolved hyperm
Neurotology disorders such as vertigo, tinnitus, and hearing loss affect a significant proportion of the population (estimated 39 million in the United States with moderate to severe symptoms).Yet no pharmacological treatments have been developed, in part due to limitations in effective drug delivery to the anatomically protected Yoto Headphones in
With the advent of the cloud computing era, big data technology has also developed rapidly.Due to the huge volume, variety, fast processing speed and low value density of big data, traditional data storage, extraction, transformation and analysis technologies are not suitable, so new solutions for big Drinks Set data application technologies are ne
The ZG40Cr20Ni20Alx (x = 0, 1.76, 3.45, and 5.34) heat-resistant steel has been newly developed on the basis of HK40 steel for aggressive oxidizing environments.The results reveal that the Al greatly enhances the oxidation resistance of ZG40Cr20Ni20 steel at high temperatures.The mass gain of ZG40Cr20Ni20 upon oxidation at 1100 °C for 480 h is